Open access publications

Following articles from the SAPALDIA project are freely accessible from the net :

Imboden M, Schwartz J, Schindler C, Curjuric I, Berger W, Liu LJS, Russi EW, Ackermann-Liebrich U, Rochat T, Probst-Hensch N. Decreased PM10 Exposure attenuates age-related lung function decline: genetic variants in p53, p21, and CCND1 modify this effect. Environ Health Perspect 2009, 117, 1420-1427.
http://ehp03.niehs.nih.gov/article/info:doi/10.1289/ehp.0800430

Ackermann-Liebrich U, Schindler C, Frei P, Probst-Hensch NM, Imboden M, Gemperli A, Rochat T, Schmid-Grendelmeier P, Bircher AJ. Sensitisation to Ambrosia in Switzerland : a public health threat on the wait. Swiss Med Wkly. 2009, 139, 70-5.
http://www.smw.ch/index.php?id=523&url=/docs/pdfcontent/smw-12489.pdf

Schindler C , Keidel D, Gerbase MW, Zemp E, Bettschart R, Brändli O, Brutsche MH, Burdet L, Karrer W, Knöpfli B, Pons M, Schwartz J, Rapp R, Liu LJS, Bayer-Oglesby L, Künzli N, Ackermann-Liebrich U, Rochat T. Improvements in PM10-exposure and reduced rates of respiratory symptoms in a cohort of Swiss adults (SAPALDIA-study). Am J Respir Crit Care Med. 2009, 179, 579-87 http://ajrccm.atsjournals.org/cgi/content/full/179/7/579

Probst-Hensch NM, Imboden M, Felber Dietrich D, Barthélemy JC, Ackermann-Liebrich U, Berger W, Gaspoz JM, Schwartz J. Glutathione S-transferase polymorphisms, passive smoking, obesity, and heart rate variability in non-smokers. Environ Health Perspect 2008, 116, 1494-1499.
http://www.ncbi.nlm.nih.gov/pubmed/19057702

Felber Dietrich D, Gemperli A, Gaspoz JM, Schindler C, Sally Liu LJ, Gold DR, Schwartz J, Rochat T, Barthélémy JC, Pons M, Roche F, Probst Hensch NM, Bridevaux PO, Gerbase MW, Neu U, Ackermann-Liebrich U and the SAPALDIA Team. Differences in Heart Rate Variability Associated with Longterm Exposure to NO2. Environ Health Perspect 2008, 116, 1357-1361.
http://www.ehponline.org/members/2008/11377/11377.pdf

Senn O, Russi EW, Schindler C, Imboden M, von Eckardstein A, Brandli O, Zemp E, Ackermann-Liebrich U, Berger W, Rochat T, Luisetti M, Probst-Hensch NM. Circulating alpha1-antitrypsin in the general population: Determinants and association with lung function. Respir Res 2008, 9, 35.
http://respiratory-research.com/content/pdf/1465-9921-9-35.pdf

Puhan MA, Gaspoz JM, Bridevaux PO, Schindler C, Ackermann-Liebrich U, Rochat T, Gerbase MW. Comparing a disease-specific and a generic health-related quality of life instrument in subjects with asthma from the general population. Health Qual Life Outcomes 2008, 6, 15.   
http://www.hqlo.com/content/pdf/1477-7525-6-15.pdf

Downs S, Schindler C, Liu LJS, Keidel D, Bayer-Oglesby L, Brutsche M, Gerbase ME, Keller R, Künzli N, Leuenberger P, Probst-Hensch N, Tschopp JM, Zellweger JP, Rochat T, Schwartz J, Ackermann-Liebrich U.
Reduction in PM10 attenuates age-related lung function decline in adults.
N Engl J Med 2007, 2338-2347.
http://content.nejm.org/cgi/reprint/357/23/2338.pdf

Liu LJS, Curjuric I, Keidel D, Heldstab J, Künzli N, Bayer-Oglesby L, Ackermann-Liebrich U, Schindler C, SAPALDIA Team. Characterization of source-specific air pollution exposure for a large population-based swiss cohort (SAPALDIA). Environ Health Perspect 2007, 115, 1638-1645.   
http://www.ehponline.org/members/2007/10177/10177.pdf

Felber Dietrich D, Schwartz J, Schindler C, Gaspoz JM, Barthelemy JC, Tschopp JM, Roche F, Von Eckardstein A, Brändli O, Leuenberger P, Gold DR, Ackermann-iebrich U, SAPALDIA Team (2007). Effect of passive smoking on heart rate ariability, heart rate and blood pressure: an observational study. Int J Epidemiology 2007, 36, 834-840.  
http://ije.oxfordjournals.org/cgi/reprint/36/4/834?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext

Imboden M, Downs SH, Senn O, Matyas G, Brändli O, Russi EW, Schindler C, Ackermann-Liebrich U, Berger W, Probst-Hensch NM, Sapaldia Team TS. Glutathione S-transferase genotypes modify lung function decline in the general population: SAPALDIA cohort study. Respir Res 2007, 8, 2.  
http://respiratory-research.com/content/pdf/1465-9921-8-2.pdf

Gerbase MW, Schindler C, Zellweger JP, Künzli N, Downs SH, Brändli O, Schwartz J, Frey M, Burdet L, Rochat T, Ackermann-Liebrich U, Leuenberger P. Respiratory effects of environmental tobacco exposure are enhanced by bronchial hyperreactivity. Am J Respir Crit Care Med 2006, 174, 1125-31.
http://ajrccm.atsjournals.org/cgi/reprint/174/10/1125?maxtoshow=&HITS=10&hits=10&RESULTFORMAT
=&author1=gerbase+mw&searchid=1&FIRSTINDEX=
0&resourcetype=HWCIT 

Bayer-Oglesby L, Schindler C, Hazenkamp-von Arx ME, Braun-Fahrlander C, Keidel D, Rapp R, Kunzli N, Braendli O, Burdet L, Sally Liu LJ, Leuenberger P, Ackermann-Liebrich U. Living near main streets and respiratory symptoms in adults. Am J Epidemiol 2006, 164, 1190-1198.  
http://aje.oxfordjournals.org/cgi/reprint/164/12/1190?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=bayer-oglesby+l&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

Chinn S, Downs SH, Anto JM, Gerbase MV, Leynaert B, de Marco R, Janson C, Jarvis D, Künzli N, Sunyer J, Svanes C, Zemp E,  Ackermann-Liebrich U, Burney P. On behalf of the ECRHS and SAPALDIA teams. Incidence of asthma and net change in symptoms in relation to changes in obesity. Eur Respir J 2006, 28, 763-771. 
http://erj.ersjournals.com/cgi/reprint/28/4/763?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1=
chinn+s&searchid=1&FIRSTINDEX=0&sortspec=relevance
&resourcetype=HWCIT

Dietrich DF, Schindler C, Schwartz J, Barthellemy JC, Tschopp JM, Roche F, von Eckardstein A, Brandli O, Leuenberger P, Gold DR, Gaspoz JM, Ackermann-Liebrich U, SAPALDIA team. Heart rate variability in an ageing population and its association with lifestyle and cardiovascular risk factors: results of the SAPALDIA study. Europace 2006, 8, 521-9 
http://europace.oxfordjournals.org/cgi/reprint/8/7/521?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&
fulltext=dietrich+felber+d&searchid=1&FIRSTINDEX=0&resourcetype
=HWCIT

Imboden M, Nieters A, Bircher A, Brutsche M, Becker N, Wjst M, Ackermann-Liebrich U, Berger W, Probst-hentsch N, SAPALDIA team. Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA). Clin Mol Allergy 2006 4,9.  
http://www.clinicalmolecularallergy.com/content/pdf/1476-7961-4-9.pdf

Nitsch D, Felber Dietrich D, von Eckardstein A, Gaspoz JM, Downs SH, Leuenberger P, Tschopp JM, Brändli O, Keller R, Gerbase MW, Probst-Hensch N, Zemp Stutz E, Ackermann-Liebrich U and SAPALDIA team. Prevalence of renal impairment and its association with cardiovascular risk factors in a general population: results of the Swiss SAPALDIA study. Nephrol Dial Transplant 2006, 21, 935-944. 
http://ndt.oxfordjournals.org/cgi/reprint/21/4/935?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext
=felber+dietrich+d&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

Senn O, Russi EW, Imboden M, Probst-Hensch NM. Alpha1-Antitrypsin Deficiency and Lung Disease: Risk modification by occupational and environmental inhalants. Eur Respir J 2005, 26, 909-917.  
http://erj.ersjournals.com/cgi/reprint/26/5/909?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1
=senn+o&searchid=1&FIRSTINDEX=0&sortspec=relevance
&resourcetype=HWCIT

Downs SH, Brändli O, Zellweger JP, Schindler Ch, Künzli N, Gerbase MW, Burdet L, Bettschart R, Zemp E, Frey M, Keller R, Tschopp JM, Leuenberger Ph, Ackermann-Liebrich U for the SAPALDIA team. Accelerated decline in lung function in smoking women with airway obstruction. Resp Res 2005, 6, 45.
http://respiratory-research.com/content/pdf/1465-9921-6-45.pdf

Jayet PY, Schindler Ch, Schwartz J, Künzli N, Zellweger JP, Brändli O, Perruchoud AP, Keller R., Schwartz J, Ackermann-Liebrich U, Leuenberger Ph and SAPALDIA team. Reference values for methacholine reactivity (SAPALDIA study). Respiratory Research 2005, 6, 131.
http://respiratory-research.com/content/pdf/1465-9921-6-131.pdf

Künzli N, Kuna-Dibbert B, Keidel D, Keller R, Brändli O, Schindler Ch, Schweinzer KM, Leuenberger Ph, Ackermann-Liebrich U, on behalf of the SAPALDIA team. Longitudinal validity of spirometers - a challenge in longitudinal studies. Swiss Med Wkly 2005, 135, 503-508.
http://www.smw.ch/dfe/set_suche.html

Schwartz J, Schindler Ch, Zemp E, Perruchoud AP, Zellweger JP, Wüthrich B, Leuenberger Ph, Ackermann-Liebrich U. Predictors of methacholine responsiveness in a general population. CHEST 2002, 122,812-820.
http://www.chestjournal.org/cgi/reprint/122/3/812?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1=schwartz+
j&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT

Schindler C, Künzli N, Bongard JP, Leuenberger Ph, Karrer W, Rapp R, Monn Ch, Ackermann-Liebrich U, and The Swiss Study on Air Pollution and Lung Diseases in Adults Investigators. Short-term variation in air pollution and in average lung function among never-smokers. AM J Respir Crit Care Med 2001, 163, 356-361.
http://ajrccm.atsjournals.org/cgi/reprint/163/2/356?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1=
schindler+c&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

Sistek D, Tschopp JM, Schindler C, Brutsche M, Ackermann-Liebrich U, Perruchoud AP, Leuenberger Ph and SAPALDIA team. Clinical diagnosis of current asthma: predictive value of respiratory symptoms in the SAPALDIA study. Eur Respir J 2001, 17, 214-219
http://erj.ersjournals.com/cgi/reprint/17/2/214?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1
=sistek+d&searchid=1&FIRSTINDEX=0&sortspec=relevance&
resourcetype=HWCIT

Künzli N, Ackermann-Liebrich U, Brändli O, Tschopp J-M, Schindler C, Leuenberger Ph, on behalf of the Swiss Study on Air Pollution and Lung Disease in Adults (SAPALDIA-team). Clinically „small" effects of air pollution on FVC have a larger public health impact. Eur Respir 2000, 15, 131-136
http://erj.ersjournals.com/cgi/reprint/15/1/131?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1=k%FCnzli+n&searchid=1&FIRSTINDEX=0&sortspec=relevance&
resourcetype=HWCIT

Leuenberger Ph, Ackermann-Liebrich U, Künzli N, Schindler Ch, Perruchoud AP et groupe SAPALDIA. SAPALDIA: passé, présent et avenir. Schweiz Med Wochenschr 2000, 130, 291-7.
http://www.smw.ch/docs/pdf/2000_08/2000-08-305.pdf

Oglesby L, Künzli N, Monn Ch, Schindler Ch, Ackermann-Liebrich U, Leuenberger Ph and the SAPALDIA-Team. Validity of annoyance scores for estimation of long term air pollution exposure in epidemiologic studies. Am J Epidemiol 2000, 152, 75-83.
http://aje.oxfordjournals.org/cgi/reprint/152/1/75?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=oglesby
+l&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

Ackermann-Liebrich U. Umwelt- und Gesundheitsforschung in der Schweiz : ein Rückblick auf das nationale Forschungsprogramm 26A. Umweltmed Forsch Prax 1999, 5, 45-51.
http://www.ecomed-medizin.de/sj/ufp/Pdf/aId/999

Künzli N, Zemp Stutz E, Perruchoud AP, Brändli O, Tschopp JM, Bolognini G, Karrer W, Schindler Ch, Ackermann-Liebrich U, Leuenberger Ph for the SAPALDIA Team. Peak flow variability in the SAPALDIA study and its validity in screening for asthma-related conditions. Am J Respir Care Med 1999, 160, 427-434
http://ajrccm.atsjournals.org/cgi/reprint/160/2/427?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&titleabstract
=peak+flow+variability&searchid=1&FIRSTINDEX=
0&resourcetype=HWCIT

Zemp E, Elsasser S, Schindler Ch, Künzli N, Perruchoud AP, Domenighetti G, Medici T, Ackermann-Liebrich U, Leuenberger Ph, Monn Ch, Bolognini G, Bongard JP, Brändli O, Karrer W, Keller R, Schöni MH, Tschopp JM, Villiger B, Zellweger JP and the SAPALDIA-Team. Long term ambient air pollution and respiratory symptoms in adults (SAPALDIA study). Am J Respir Crit Care Med 1999, 159, 1257-1266
http://ajrccm.atsjournals.org/cgi/reprint/159/4/1257?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1=zemp
+e&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

Kaiser R, Schindler C, Künzli N, Ackermann-Liebrich U, Heeb D, Medici TC, Zellweger JP and the SAPALDIA Team. Use of transition probabilities to estimate the effect of smoking on the duration of episodes of respiratory symptoms in diary data. American Journal of Epidemiology 1998, 148, 600-608.
http://aje.oxfordjournals.org/cgi/reprint/148/6/600?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=use
+of+transition+probabilities+to+estimate&searchid=1&FIRSTINDEX
=0&resourcetype=HWCIT

Künzli N, Ackermann-Liebrich U, Keller R, Perruchoud AP, Schindler C, SAPALDIA team. Variability of FVC and FEV1 due to technician, team, device and subject in an eight centres study: three quality control studies in SAPALDIA. Eur Respir J 1995, 8, 371-376.
http://erj.ersjournals.com/cgi/reprint/8/3/371?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1=k%FCnzli+n&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&
sortspec=relevance&resourcetype=HWCIT