List of SAPALDIA publications in medical journals

  1. Leuenberger Ph. Pollution de l'air et maladies respiratoires: la situation en Suisse. Tribuna Medica Ticinese 1992, 57, 696-698.
  2. Ackermann-Liebrich U und SAPALDIA-Team. Schweizer Studie Luftverschmutzung und Atemwegserkrankungen bei Erwachsenen - SAPALDIA. Atemwegs- Lungenkrankheiten 1993; 5, 190-194.
  3. Monn Ch. Staubförmige Verunreinigung der Luft. Allergologie 1994, 11, 509-513.
  4. Leuenberger Ph, Schwartz J, Ackermann-Liebrich U, Blaser K, Bolognini G, Bongard JP, Brändli O, Braun P, Bron C, Brutsche M, Domenighetti G, Elsasser S, Guldimann P, Hollenstein C, Hufschmid P, Karrer W, Keller R, Keller-Wossidlo H, Künzli N, Luthi JC, Martin BW, Medici T, Perruchoud AP, Radaelli A, Schindler C, Schöni MH, Solari G, Tschopp JM, Villiger B, Wüthrich B, Zellweger JP, Zemp E (Swiss study on air pollution and lung disease in adults, SAPALDIA-Team). Passive smoking exposure in adults and chronic respiratory symptoms (SAPALDIA study). Am J Respir Crit Care Med 1994, 150, 1221-1228.
  5. Wüthrich B. Epidemiologie IgE-vermittelter Allergien. Hautnah Schweiz 1995, 6,12-13.
  6. Wüthrich B, Schindler Ch, Leuenberger Ph, Ackermann-Liebrich U and SAPALDIA-Team. Prevalence of atopy and pollinosis in the adult population of Switzerland (SAPALDIA study). Int Arch Allergy Immunol 1995, 106, 149-156.
  7. Wüthrich B, Schindler C, Leuberger Ph, Ackermann-Liebrich U, Zellweger JP und SAPALDIA Team. Prävalenz der Pollinose unter besonderer Berücksichtigung der Schweiz (SAPALDIA Studie). Kongressband Stiftung Deutscher Polleninformationsdienst. 3. europäischen Pollenflug Symposium (4. - 6. Februar 1994).
  8. Monn Ch, Brändli O, Schaeppi G, Schindler Ch, Ackermann-Liebrich U, Leuenberger Ph and SAPALDIA Team. Particulate matter <10 *g/m3 (PM10) and total suspended particulates (TSP) in urban, rural and alpine air in Switzerland. Atmospheric Environment 1995, 29, 2565-2573.
  9. Leuenberger Ph. Asthme bronchique et pollution atmosphérique. Médecine et Environment 1995; 53 (Bezug zur SAPALDIA-Studie)
  10. Leuenberger Ph et groupe SAPALDIA. Pollution de l'air en Suisse et maladies respiratoires chez l'adulte. Résultats préliminaires de la partie transversale de l'étude SAPALDIA. Praxis 1995, 84, 1096-1100.
  11. Künzli N, Ackermann-Liebrich U, Keller R, Perruchoud AP, Schindler C, SAPALDIA team. Variability of FVC and FEV1 due to technician, team, device and subject in an eight centres study: three quality control studies in SAPALDIA. Eur Respir J 1995, 8, 371-376.
  12. Wüthrich B, Schindler C, Medici TC, Zellweger JP, Leuenberger Ph and SAPALDIA-Team. IgE levels, atopy markers and hay fever in relation to age, sex and smoking status in a normal adult swiss population. Int Arch Allergy Immunol 1996, 111, 396-40
  13. Leuenberger Ph. Letter to the Editor. Passive smoking exposure in adults and chronic respiratory symptoms (SAPALDIA study). Am J Respir Crit Care Med 1996, 153, 462-463
  14. Hegner H, Monn Ch, Stahel W, Leuenberger Ph, Ackermann-Liebrich U, Wanner H-U und SAPALDIA-Team. Kleinräumige Verteilung von Stickstoffdioxid. Gesundheits- und Umwelt-technik 1996, 4, 3-7.
  15. Brändli O, Schindler C, Künzli N, Keller R, Perruchoud AP and SAPALDIA team. Lung function in healthy never smoking adults: reference values and lower limits of normal of a Swiss population. Thorax 1996, 51, 277-283.
  16. Strupler W, Wüthrich B, Schindler C und SAPALDIA-Team. Prävalenz der Hymenopterengiftallergien in der Schweiz: eine epidemiologische und serologische Studie der SAPALDIA -Stichprobe. Allergo J 1997, 6, 7-11.
  17. Martin BW, Ackermann-Liebrich U, Leuenberger Ph, Künzli N, Zemp Stutz E, Keller R, Zellweger JP, Wüthrich B, Monn Ch, Blaser K, Bolognini G, Bongard JP, Brändli O, Braun P, Defila C, Domenighetti G, Grize L, Karrer W, Keller-Wossidlo H, Medici TC, Peeters A, Perruchoud AP, Schindler C, Schoeni MH, Schwartz J, Solari G, Tschopp JM, Villiger B (SAPALDIA-Team). SAPALDIA-methods and participation in the cross-sectional part of the Swiss Study on Air pollution and Lung Diseases in Adults. Soz Präventivmed 1997, 42, 67-84.
  18. Luthi JC, Zellweger JP, Grize L, Leuenberger Ph, Ackermann-Liebrich U et SAPALDIA Team. Etude du biais dû aux non-répondants dans une étude épidémiologique (SAPALDIA). Soz Präventiv-med 1997, 42, 85-94.
  19. Künzli N. SAPALDIA-Studie - keine Resultate? Soz Präventivmed 1997, 42, 131-132.
  20. Ackermann-Liebrich U, Leuenberger Ph, Schwartz J, Schindler C, Monn Ch, Bolognini G, Bongard JP, Brändli O, Domenighetti G, Elsasser S, Grize L, Karrer W, Keller R, Keller-Wossidlo H, Künzli N, Martin BW, Medici TC, Perruchoud AP, Schöni MH, Tschopp JM, Villiger B, Wüthrich B, Zellweger JP, Zemp E and SAPALDIA-Team. Lung function and long term exposure to air pollutants in Switzerland. Am J Respir Crit Care Med 1997, 155, 122-129.
  21. Tschopp JM, Sistek D, Schindler Ch, Leuenberger Ph, Perruchoud AP, Wüthrich B, Brutsche M, Zellweger JP, Karrer W, Brändli O, SAPALDIA team. Current allergic asthma and rhinitis: diagnostic efficiency of three commonly used atopic markers (IgE, skin prick tests, and Phadiatop). Result from 8329 randomized adults from the SAPALDIA study. Allergy 1998, 53, 608-613.
  22. Schindler Ch, Ackermann-Liebrich U, Leuenberger Ph, Monn Ch, Rapp R, Bolognini G, Bongard JP, Brändli O, Domenighetti G, Karrer W, Keller R, Tullio G, Medici TG, Perruchoud AP, Schöni MH, Jean-Marie Tschopp JM, Villiger B, Zellweger JP and SAPALDIA-Team. Associations between lung function and estimated average exposure to NO2 in 8 areas of Switzerland (SAPALDIA). Epidemiology 1998, 9, 405-411.
  23. Monn Ch, Brändli O, Schindler Ch, Ackermann-Liebrich U, Leuenberger Ph and SAPALDIA Team. Personal exposure to nitrogen dioxide in Switzerland. The Science of the Total Environment 1998, 215, 243-251.
  24. Kaiser R, Schindler C, Künzli N, Ackermann-Liebrich U, Heeb D, Medici TC, Zellweger JP and the SAPALDIA Team. Use of transition probabilities to estimate the effect of smoking on the duration of episodes of respiratory symptoms in diary data. American Journal of Epidemiology 1998, 148, 600-608.
  25. Leuenberger Ph, Künzli N, Ackermann-Liebrich U, Schindler Ch, Bolognini G, Bongard JP, Brändli O, Defila C, Domenighetti G, Karer W, Keller R, Medici T, Monn Ch, Perruchoud AP, Schöni M, Tschopp JM, Villiger B, Wüthrich B, Zellweger JP et groupe SAPALDIA. Etude suisse sur la pollution de l'air et les maladies respiratoires chez l'adulte (SAPALDIA). Schweiz Med Wochenschr 1998, 128, 150-161.
  26. Zemp E, Elsasser S, Schindler Ch, Künzli N, Perruchoud AP, Domenighetti G, Medici T, Ackermann-Liebrich U, Leuenberger Ph, Monn Ch, Bolognini G, Bongard JP, Brändli O, Karrer W, Keller R, Schöni MH, Tschopp JM, Villiger B, Zellweger JP and the SAPALDIA-Team. Long term ambient air pollution and respiratory symptoms in adults (SAPALDIA study). Am J Respir Crit Care Med 1999, 159, 1257-1266
  27. Wüthrich B, Leuenberger Ph, Ackermann-Liebrich U, Schindler Ch, Karrer W, Künzli N, Brändli O und SAPALDIA Team. Atopische Sensibilisierung, Luftverschmutzung und respiratorische Erkrankungen in der Schweiz (SAPALDIA Studie). Allergologie 1999, 5, 267-274
  28. Monn Ch, Alean-Kirkpatrick P, Künzli N, Defila C, Peeters A, Ackermann-Liebrich U, Leuenberger Ph, SAPALDIA Team. Short Communication, Air Pollution, climate and pollen comparisons in urban, rural and alpine regions in Switzerland (SAPALDIA Study). Atmospheric Environment 1999, 33, 2411-2416
  29. Künzli N, Zemp Stutz E, Perruchoud AP, Brändli O, Tschopp JM, Bolognini G, Karrer W, Schindler Ch, Ackermann-Liebrich U, Leuenberger Ph for the SAPALDIA Team. Peak flow variability in the SAPALDIA study and its validity in screening for asthma-related conditions. Am J Respir Care Med 1999, 160, 427-434
  30. Ackermann-Liebrich U. Umwelt- und Gesundheitsforschung in der Schweiz : ein Rückblick auf das nationale Forschungsprogramm 26A. Umweltmed Forsch Prax 1999, 5, 45-51.
  31. Wyler C, Braun-Fahrländer C, Künzli N, Schindler Ch, Ackermann-Liebrich U, Perruchoud AP, Leuenberger Ph, Wüthrich B and the Swiss Study on Air Pollution and Lung Disease in Adults (SAPALDIA) Team. Exposure to motor vehicle traffic and allergic sensitization. Epidemiology 2000, 1,450-456
  32. Oglesby L, Künzli N, Monn Ch, Schindler Ch, Ackermann-Liebrich U, Leuenberger Ph and the SAPALDIA-Team. Validity of annoyance scores for estimation of long term air pollution exposure in epidemiologic studies. Am J Epidemiol 2000, 152, 75-83.
  33. Leuenberger Ph, Ackermann-Liebrich U, Künzli N, Schindler Ch, Perruchoud AP et groupe SAPALDIA. SAPALDIA: passé, présent et avenir. Schweiz Med Wochenschr 2000, 130, 291-7.
  34. Leuenberger Ph, Schindler Ch, Schwartz J, Ackermann-Liebrich U, Tara D, Perruchoud AP, Wüthrich B, Zellweger JP, Blaser K, Bolognini G, Bongard JP, Brändli O, Domenighetti G, Elsasser S, Grize L, Karrer W, Keller R, Künzli N, Medici T, Schöni MH, Solari G, Tschopp JM, Villiger B, Zemp E. Occupational exposure to inhalative irritants and methacholine responsiveness. Scand J Work Environ Health 2000, 26, 146-152
  35. Künzli N, Schwartz J, Zemp Stutz E, Ackermann-Liebrich U, Leuenberger Ph on behalf of the SAPALDIA Team. Association of environmental tobacco smoke at work and forced expiratory lung function among never smoking asthmatics and non-asthmatics. Soz.-Präventivmed 2000, 45, 208-217
  36. Künzli N, Ackermann-Liebrich U, Brändli O, Tschopp J-M, Schindler C, Leuenberger Ph, on behalf of the Swiss Study on Air Pollution and Lung Disease in Adults (SAPALDIA-team). Clinically „small" effects of air pollution on FVC have a larger public health impact. Eur Respir 2000, 15, 131-136
  37. Brändli O, Schindler Ch, Leuenberger Ph, Baur X, Degens P, Künzli N, Perruchoud AP. Re-estimated equations for 5th percentiles of lung function variables. THORAX 2000, 55, 173-174.
  38. Sistek D, Tschopp JM, Schindler C, Brutsche M, Ackermann-Liebrich U, Perruchoud AP, Leuenberger Ph and SAPALDIA team. Clinical diagnosis of current asthma: predictive value of respiratory symptoms in the SAPALDIA study. Eur Respir J 2001, 17, 214-219
  39. Schindler C, Künzli N, Bongard JP, Leuenberger Ph, Karrer W, Rapp R, Monn Ch, Ackermann-Liebrich U, and The Swiss Study on Air Pollution and Lung Diseases in Adults Investigators. Short-term variation in air pollution and in average lung function among never-smokers. AM J Respir Crit Care Med 2001, 163, 356-361.
  40. Danuser B, Weber C, Künzli N, Schindler C and Nowak D. Respiratory symptoms in swiss farmers: an epidemiological study of risk factors. Am J Ind Med 2001, 39, 410-418.
  41. Schwartz J, Schindler Ch, Zemp E, Perruchoud AP, Zellweger JP, Wüthrich B, Leuenberger Ph, Ackermann-Liebrich U. Predictors of methacholine responsiveness in a general population. CHEST 2002, 122,812-820.
  42. Künzli N, Kuna-Dibbert B, Keidel D, Keller R, Brändli O, Schindler Ch, Schweinzer KM, Leuenberger Ph, Ackermann-Liebrich U, on behalf of the SAPALDIA team. Longitudinal validity of spirometers - a challenge in longitudinal studies. Swiss Med Wkly 2005, 135, 503-508.
  43. Jayet PY, Schindler Ch, Schwartz J, Künzli N, Zellweger JP, Brändli O, Perruchoud AP, Keller R., Schwartz J, Ackermann-Liebrich U, Leuenberger Ph and SAPALDIA team. Reference values for methacholine reactivity (SAPALDIA study). Respiratory Research 2005, 6, 131.
  44. Downs SH, Brändli O, Zellweger JP, Schindler Ch, Künzli N, Gerbase MW, Burdet L, Bettschart R, Zemp E, Frey M, Keller R, Tschopp JM, Leuenberger Ph, Ackermann-Liebrich U for the SAPALDIA team. Accelerated decline in lung function in smoking women with airway obstruction. Resp Res 2005, 6, 45.
  45. Ackermann-Liebrich U, Kuna-Dibbert B, Probst-Hensch NM, Schindler Ch, Felber Dietrich D, Zemp Stutz E, Bayer-Oglesby L, Baum F, Brändli O, Brutsche M, Downs SH, Keidel D, Gerbase MW, Imboden M, Keller R, Knöpfli B, Künzli N, Nicod L, Pons M, Städele P, Tschopp JM, Zellweger JP, Leuenberger Ph and SAPALDIA team. Follow-up of the swiss cohort study on air pollution and lung diseases in adults (SAPALDIA 2) 1991-2003: Methods and characterization of participants. Soz.-Präventivmed 2005, 50, 245-263.
  46. Senn O, Russi EW, Imboden M, Probst-Hensch NM. Alpha1-Antitrypsin Deficiency and Lung Disease: Risk modification by occupational and environmental inhalants. Eur Respir J 2005, 26, 909-917.
  47. Jayet PY, Schindler C, Schwartz J, Künzli N, Zellweger JP, Ackermann-Liebrich, Leuenberger P and SAPALDIA team. Passive smoking exposure among adults and the dynamics of respiratory symptoms in a prospective multicenter cohort study. Scand J Work Environ Health 2005, 31, 465-473.
  48. Nitsch D, Felber Dietrich D, von Eckardstein A, Gaspoz JM, Downs SH, Leuenberger P, Tschopp JM, Brändli O, Keller R, Gerbase MW, Probst-Hensch N, Zemp Stutz E, Ackermann-Liebrich U and SAPALDIA team. Prevalence of renal impairment and its association with cardiovascular risk factors in a general population: results of the Swiss SAPALDIA study. Nephrol Dial Transplant 2006, 21, 935-944.
  49. Imboden M, Nicod L, Nieters A, Glaus E, Matyas G, Bircher A, Ackermann-Liebrich U, Berger W, Probst-hentsch N, SAPALDIA team. The common G-allele of interleukin-18 single-nucleotide polymorphism is a genetic risk factor for atopic asthma. The SAPALDIA Cohort Study. Clin Exp Allergy 2006, 36, 211-8.
  50. Imboden M, Nieters A, Bircher A, Brutsche M, Becker N, Wjst M, Ackermann-Liebrich U, Berger W, Probst-hentsch N, SAPALDIA team. Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA). Clin Mol Allergy 2006 4,9.
  51. Felber Dietrich D, Schindler C, Schwartz J, Barthellemy JC, Tschopp JM, Roche F, von Eckardstein A, Brändli O, Leuenberger P, Gold DR, Gaspoz JM, Ackermann-Liebrich U, SAPALDIA team. Heart rate variability in an ageing population and its association with lifestyle and cardiovascular risk factors: results of the SAPALDIA study. Europace 2006, 8, 521-9.
  52. Brutsche MH, Downs SH, Schindler C, Gerbase MW, Schwartz J, Frey M, Russi EW, Ackermann-Liebrich U, Leuenberger P. Bronchial hyperresponsiveness and the development of asthma and COPD in asymptomatic individuals: SAPALDIA Cohort Study. Thorax 2006, 61, 671-7.
  53. Chinn S, Downs SH, Anto JM, Gerbase MV, Leynaert B, de Marco R, Janson C, Jarvis D, Künzli N, Sunyer J, Svanes C, Zemp E,  Ackermann-Liebrich U, Burney P. On behalf of the ECRHS and SAPALDIA teams. Incidence of asthma and net change in symptoms in relation to changes in obesity. Eur Respir J 2006, 28, 763-771.
  54. Bayer-Oglesby L, Schindler C, Hazenkamp-von Arx ME, Braun-Fahrlander C, Keidel D, Rapp R, Kunzli N, Braendli O, Burdet L, Sally Liu LJ, Leuenberger P, Ackermann-Liebrich U. Living near main streets and respiratory symptoms in adults. Am J Epidemiol 2006, 164, 1190-1198.
  55. Gerbase MW, Schindler C, Zellweger JP, Künzli N, Downs SH, Brändli O, Schwartz J, Frey M, Burdet L, Rochat T, Ackermann-Liebrich U, Leuenberger P. Respiratory effects of environmental tobacco exposure are enhanced by bronchial hyperreactivity. Am J Respir Crit Care Med 2006, 174, 1125-31.
  56. Imboden M, Downs SH, Senn O, Matyas G, Brändli O, Russi EW, Schindler C, Ackermann-Liebrich U, Berger W, Probst-Hensch NM, Sapaldia Team TS. Glutathione S-transferase genotypes modify lung function decline in the general population: SAPALDIA cohort study. Respir Res 2007, 8, 2.
  57. Graf N, Johansen P, Schindler C, Wuthrich B, Ackermann-Liebrich U, Gassner M, Kundig TM, Senti G. Analysis of the relationship between pollinosis and date of birth in Switzerland. Int Arch Allergy Immunol 2007, 143, 269-75.
  58. Felber Dietrich D, Schwartz J, Schindler C, Gaspoz JM, Barthelemy JC, Tschopp JM, Roche F, Von Eckardstein A, Brändli O, Leuenberger P, Gold DR, Ackermann-iebrich U, SAPALDIA Team (2007). Effect of passive smoking on heart rate ariability, heart rate and blood pressure: an observational study. Int J Epidemiology 2007, 36, 834-840.
  59. Dratva J, Zemp E, Staedele P, Schindler C, Constanza M, Gerbase MW, Probst-Hensch N, Rochat T, Ackermann-Liebrich U, SAPALDIA team. Variability of reproductive history across the Swiss SAPALDIA cohort - Pattern and main determinants. Ann Hum Biol 2007, 34, 437-453.
  60. Bridevaux PO, Cornuz J, Gaspoz JM, Burnand B, Ackermann-Liebrich U, Schindler C, Leuenberger P, Rochat T, Gerbase MW. Secondhand smoke and health-related quality of life in never smokers results from the SAPALDIA Cohort Study 2 . Arch Intern Med 2007, 167, 2516-2523.
  61. Liu LJS, Curjuric I, Keidel D, Heldstab J, Künzli N, Bayer-Oglesby L, Ackermann-Liebrich U, Schindler C, SAPALDIA Team. Characterization of source-specific air pollution exposure for a large population-based swiss cohort (SAPALDIA). Environ Health Perspect 2007, 115, 1638-1645.
  62. Downs S, Schindler C, Liu LJS, Keidel D, Bayer-Oglesby L, Brutsche M, Gerbase ME, Keller R, Künzli N, Leuenberger P, Probst-Hensch N, Tschopp JM, Zellweger JP, Rochat T, Schwartz J, Ackermann-Liebrich U. Reduction in PM10 attenuates age-related lung function decline in adults. N Engl J Med 2007, 357, 2338-2347.
  63. Imboden M, Rochat T, Brutsche M, Schindler C, Downs SH, Gerbase MW, Berger W, Probst-Hensch NM and the SAPALDIA Team. Glutathione-S transferase genotype increases risk of progression from bronchial hyperresponsiveness to asthma in adults.Thorax, 2008, 63, 322-8.
  64. Puhan MA, Gaspoz JM, Bridevaux PO, Schindler C, Ackermann-Liebrich U, Rochat T, Gerbase MW. Comparing a disease-specific and a generic health-related quality of life instrument in subjects with asthma from the general population. Health Qual Life Outcomes 2008, 6, 15.
  65. Castro-Giner F, Kogevinas M, Mächler M, De Cid R, Van Steen K, Imboden M, Schindler C, Berger W, Gonzalez JR, Franlin KA, Janson C, Jarvis D, Omenaas E, Burney P, Rochat T, Estivill X, Anto JM, Wjst M, Probst-Hensch NM.. TNFA-308 in two International population-based cohorts shows increased risk for asthma. Eur Respir J, 2008, 32, 350-361.
  66. Bridevaux PO, Gerbase MW, Probst-Hensch NM, Schindler C, Gaspoz JM and Rochat  T. COPD, Long term lung function decline, utilization of care and quality of life in modified GOLD stage 1.  Thorax 2008, 63, 768-774.
  67. Senn O, Russi EW, Schindler C, Imboden M, von Eckardstein A, Brandli O, Zemp E, Ackermann-Liebrich U, Berger W, Rochat T, Luisetti M, Probst-Hensch NM. Circulating alpha1-antitrypsin in the general population: Determinants and association with lung function. Respir Res 2008, 9, 35.
  68. Zorzetto M, Russi EW, Senn O, Imboden M. Ferrarrotti I, Tinelli C, Campo I, Ottaviani S, Scabini R, Berger W, Brändli O, Rochat T, Luisetti M, Probst-Hensch NM. SerpinA1 gene variants in indivuduals from the general population with reduced alpha-1-antitrypsin serum level. Clin Chem 2008, 54, 1331-1338.
  69. Felber Dietrich D, Ackermann-Liebrich U, Schindler C, Barthélémy JC, Braendli O, Gold DR, Knoepli B, Probst-Hensch NM, Roche F, Tschopp JM, von Eckardstein A, Gaspoz JM. Effect of physical activity on heart rate variability in normal weight, overweight and obese subjects: results from the SAPALDIA study. Eur J Appl Physiol 2008, 104,557-565. 
  70. Felber Dietrich D, Gemperli A, Gaspoz JM, Schindler C, Sally Liu LJ, Gold DR, Schwartz J, Rochat T, Barthélémy JC, Pons M, Roche F, Probst Hensch NM, Bridevaux PO, Gerbase MW, Neu U, Ackermann-Liebrich U and the SAPALDIA Team. Differences in Heart Rate Variability Associated with Longterm Exposure to NO2. Environ Health Perspect 2008, 116, 1357-1361.
  71. Probst-Hensch NM, Imboden M, Felber Dietrich D, Barthélemy JC, Ackermann-Liebrich U, Berger W, Gaspoz JM, Schwartz J. Glutathione S-Transferase Polymorphisms, Passive Smoking, Obesity, and Heart Rate Variability in Non-Smokers. Environ Health Perspect 2008, 116, 1494-1499.
  72. Dratva J, Gomez Real F, Schindler C, Ackermann-Liebrich U, Gerbase MW, Probst-Hensch N, Svanes C, Raidar Omenaas E, Neukirch F, Wjst M, Morabia A, Jarvis D, Leynaert B, Zemp E. Is age at menopause increasing across Europe? Results on age at menopause and determinants from two population-based studies. Menopause 2009, 16(2):385-394.
  73. Schindler C , Keidel D, Gerbase MW, Zemp E, Bettschart R, Brändli O, Brutsche MH, Burdet L, Karrer W, Knöpfli B, Pons M, Schwartz J, Rapp R, Liu LJS, Bayer-Oglesby L, Künzli N, Ackermann-Liebrich U, Rochat T. Improvements in PM10-exposure and reduced rates of respiratory symptoms in a cohort of Swiss adults (SAPALDIA-study). Am J Respir Crit Care Med. 2009, 179, 579-87. Epub 2009 Jan 16.
  74. Castro-Giner F, Kogevinas M, Imboden M, de Cid R, Jarvis D, Mächler M, Berger W, Burney P, Franklin KA, Gonzalez JR, Heinrich J, Janson C, Omenaas E, Pin I, Rochat T, Sunyer J, Wjst M, Anto JM, Estivill X, Probst-Hensch NM. Joint effect of obesity and TNFA variability on asthma : two international cohort studies. Eur Respir J. 2009, 33, 1003-9.
  75. Mirabelli MC, Zock JP, Bircher AJ, Jarvis D, Keidel D, Kromhout H, Norback D, Olivieri M, Plana E, Radon K, Schindler C, Schmid-Grendelmeier P, Toren K, Villani S, Kogevinas M. Metalworking exposures and persistent skin symptoms in the ECRHS II and SAPALDIA 2 cohorts. Contact dermatitis. 2009; 60(5):256-63
  76. Ackermann-Liebrich U, Schindler C, Frei P, Probst-Hensch NM, Imboden M, Gemperli A, Rochat T, Schmid-Grendelmeier P, Bircher AJ. Sensitisation to Ambrosia in Switzerland : a public health threat on the wait. Swiss Med Wkly. 2009, 139, 70-5.
  77. Bridevaux PO, Gerbase MW, Schindler C, Felber Dietrich D, Curjuric I, Dratva J, Ackermann-Liebrich U, Probst-Hensch N, Gaspoz JM, Rochat T. Sex-specific effect of body weight gain on systemic inflammation in subjects with COPD. Eur Respir 2009;64:183.
  78. Künzli N, Bridevaux PO, Liu LJS, Garcia-Esteban R, Schindler C, Gerbase MW, Sunyer J, Keidel D, Rochat T and the SAPALDIA Team 2009. Traffic-related air pollution correlates with adult-onset asthma among never-smokers. Thorax, 2009, 8;64:664-70
  79. Bridevaux PO, Gerbase MW, Rochat T. Authors’ reply to « GOLD stage 1 is crying wolf » by PL Enright. Thorax 2009, 64, 183.
  80. Imboden M, Schwartz J, Schindler C, Curjuric I, Berger W, Liu LJS, Russi EW, Ackermann-Liebrich U, Rochat T, Probst-Hensch N. Decreased PM10 Exposure attenuates age-related lung function decline: genetic variants in p53, p21, and CCND1 modify this effect. Environ Health Perspect 2009, 117, 1420-1427.
  81. Bridevaux PO, Gerbase MW, Rochat T. From the authors (about : Sex forced expiratory volume in 1 s decline, body weight change and C-reactive protein in COPD patients). Eur Respir J 2009, 34, 777.
  82. Curjuric I, Imboden M, Schindler C, Downs SH, Hersberger M, Liu SL, Matyas G, W Russi E, Schwartz J, Thun GA, Postma DS, Rochat T, Probst-Hensch NM; the SAPALDIA team. HMOX1 and GST variants modify attenuation of FEF25-75-decline due to PM10 reduction. Eur Respir J. 2009: 35(3): 505-514.
  83. Probst-Hensch NM, Curjuric I, Bridevaux PO, Ackermann-Liebrich UA, Bettschart RW, Brändli O, Brutsche M, Burdet L, Gerbase MW, Knöpfli B, Künzli N, Pons MG, Schindler C, Tschopp JM, Rochat T, Russi EW. Longitudinal Change of Pre-Bronchodilator Spirometric Obstruction and Health Outcomes -Results from the Sapaldia Cohort. Thorax. 2009 :65(2):150-6
  84. Castro-Giner F, Künzli N, Jacquemin B, Forsberg B, de Cid R, Sunyer J, Jarvis D, Briggs D, Vienneau D, Norback D, Gonzalez JR, Guerra S, Janson C, Anto JM, Wjst M, Heinrich J, Estivill X & Kogevinas M. Traffic-related air pollution, oxidative stress genes, and asthma (ECHRS). Environ Health Perspect 2009; 117, 1919-1924.
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  86. Dratva J, Schindler C, Curjuric I, Stolz D, Macsali F, Gomez Real F, Zemp E. Perimenstrual increase in bronchial hyper-reactivity in premenopausal women – Results from the population-based SAPALDIA 2 cohort. J Allergy Clin Immunol 2010, 125, 823-829.
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  89. Köttgen A, Pattaro C, Boger CA, (…), Probst-Hensch NM, (…), Imboden M, Nitsch D, (…), Rochat T, (…), Fox CS. New loci associated with kidney function and chronic kidney disease. Nat Genet 2010, 42, 376-84
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  96. Liu LJS, Tsai MY, Keidel D, Gemperli A, Ineichen A, Hazenkamp-von Arx M, Bayer-Oglesby L, Rochat T, Künzli N, Ackermann-Liebrich U, Straehl P, Schwartz J & Schindler C Long-term exposure models for traffic related NO(2) across geographically diverse areas over separate years. Atmos Environ 2012 46, 460-471
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  100. Imboden M, Bouzigon E, Curjuric I, Ramasamy A, Kumar A, Hancock DB, Wilk JB, Vonk JM, Thun GA, Siroux V, Nadif R, Monier F, Gonzalez JR, Wjst M, Heinrich J, Loehr LR, Franceschini N, North KE, Altmüller J, Koppelman GH, Guerra S, Kronenberg F, Lathrop M, Moffatt MF, O'Connor GT, Strachan DP, Postma DS, London SJ, Schindler C, Kogevinas M, Kauffmann F, Jarvis DL, Demenais F & Probst-Hensch NM  Genome-wide association study of lung function decline in adults with and without asthma. J Allergy Clin Immunol 2012 129, 1218-1228
  101. Ferrarotti I, Thun GA, Zorzetto M, Ottaviani S, Imboden M, Schindler C, Von Eckardstein A, Rohrer L, Rochat T, Russi EW, Probst-Hensch NM & Luisetti M (2012) Serum levels and genotype distribution of alpha1-antitrypsin in the general population. Thorax 67, 669–674
  102. Dratva J, Phuleria HC, Foraster M, Gaspoz JM, Keidel D, Künzli N, Liu SL, Pons M, Zemp E, Gerbase MW & Schindler C  Transportation noise and blood pressure in a population-based sample of adults. Environ Health Perspect 2012 120, 50-5
  103. Artigas MS, Loth DW, Wain LV, Gharib SA, Obeidat M, Tang W, Zhai G, Zhao JH, Smith AV, Huffman JE, Albrecht E, Jackson CM, Evans DM, Cadby G, Fornage M, Manichaikul A, Lopez LM, Johnson T, Aldrich MC, Aspelund T, Barroso I, Campbell H, Cassano PA, Couper DJ, Eiriksdottir G, Franceschini N, Garcia M, Gieger C, Gislason GK, Grkovic I, Hammond CJ, Hancock DB, Harris TB, Ramasamy A, Heckbert SR, Heliovaara M, Homuth G, Hysi PG, James AL, Jankovic S, Joubert BR, Karrasch S, Klopp N, Koch B, Kritchevsky SB, Launer LJ, Liu Y, Loehr LR, Lohman K, Loos RJ, Lumley T, Al Balushi KA, Ang WQ, Barr RG, Beilby J, Blakey JD, Boban M, Boraska V, Brisman J, Britton JR, Brusselle GG, Cooper C, Curjuric I, Dahgam S, Deary IJ, Ebrahim S, Eijgelsheim M, Francks C, Gaysina D, Granell R, Gu X, Hankinson JL, Hardy R, Harris SE, Henderson J, Henry A, Hingorani AD, Hofman A, Holt PG, Hui J, Hunter ML, Imboden M, Jameson KA, Kerr SM, Kolcic I, Kronenberg F, Liu JZ, Marchini J, McKeever T, Morris AD, Olin AC, Porteous DJ, Postma DS, Rich SS, Ring SM, Rivadeneira F, Rochat T, Sayer AA, Sayers I, Sly PD, Smith GD, Sood A, Starr JM, Uitterlinden AG, Vonk JM, Wannamethee SG, Whincup PH, Wijmenga C, Williams OD, Wong A, Mangino M, Marciante KD, McArdle WL, Meibohm B, Morrison AC, North KE, Omenaas E, Palmer LJ, Pietilainen KH, Pin I, Pola Sbreve EO, Pouta A, Psaty BM, Hartikainen AL, Rantanen T, Ripatti S, Rotter JI, Rudan I, Rudnicka AR, Schulz H, Shin SY, Spector TD, Surakka I, Vitart V, Volzke H, Wareham NJ, Warrington NM, Wichmann HE, Wild SH, Wilk JB, Wjst M, Wright AF, Zgaga L, Zemunik T, Pennell CE, Nyberg F, Kuh D, Holloway JW, Boezen HM, Lawlor DA, Morris RW, Probst-Hensch N, Kaprio J, Wilson JF, Hayward C, Kahonen M, Heinrich J, Musk AW, Jarvis DL, Glaser S, Jarvelin MR, Ch Stricker BH, Elliott P, O'Connor GT, Strachan DP, London SJ, Hall IP, Gudnason V & Tobin MD Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet 43 2011, 1082-1090.
  104. Obeidat M, Wain LV, Shrine N, Soler Artigas M, Repapi E, Burton PR, Johnson T, Ramasamy A, Zhao JH, Zhai G, Huffman JE, Vitart V, Albrecht E, Igl W, Hartikainen AL, Pouta A, Cadby G, Hui J, Palmer LJ, Hadley D, McArdle WL, Rudnicka AR, Barroso I, Loos RJF, Wareham NJ, Mangino M, Soranzo N, Spector TD, Gläser S, Homuth G, Völzke H, Deloukas P, Granell R, Henderson J, Grkovic I, Jankovic S, Zgaga L, Polasek O, Rudan I, Wright AF, Campbell H, Wild SH, Wilson JF, Heinrich J, Imboden M, Probst-Hensch NM, Gyllensten U, Johansson A, Zaboli G, Mustelin L, Rantanen T, Surakka I, Kaprio J, Jarvelin MR, Hayward C, Evans DM, Koch B, Musk AW, Elliott P, Strachan DP, Tobin MD, Sayers I, Hall IP & SpiroMeta Consortium  A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample. PLoS One 2011 6, e19382
  105. Curjuric I, Imboden M, Nadif R, Kumar A, Schindler C, Haun M, Kronenberg F, Künzli N, Phuleria H, Postma DS, Russi EW, Rochat T, Demenais F & Probst-Hensch NM Different genes interact with particulate matter and tobacco smoke exposure in affecting lung function decline in the general population. PLoS One 2012 7, e40175
  106. Adam M, Felber Dietrich D, Schaffner E, Carballo D, Barthélémy JC, Gaspoz JM, Tsai MY, Rapp R, Phuleria HC, Schindler C, Schwartz J, Künzli N & Probst-Hensch NM Long-term exposure to traffic-related PM(10) and decreased heart rate variability: is the association restricted to subjects taking ACE inhibitors? Environ Int 2012 48, 9-16.
  107. Mehta AJ, Adam M, Schaffner E, Barthelemy JC, Carballo D, Gaspoz JM, Rochat T, Schindler C, Schwartz J, Zock JP, Künzli N, Probst-Hensch N & Sapaldia Team  Heart Rate Variability in Association with Frequent Use of Household Sprays and Scented Products in SAPALDIA. Environ Health Perspect 2012 120, 958-964.
  108. Conen D, Adam M, Roche F, Barthelemy JC, Felber Dietrich D, Imboden M, Künzli N, Von Eckardstein A, Regenass S, Hornemann T, Rochat T, Gaspoz JM, Probst-Hensch N & Carballo D (2012) Premature atrial contractions in the general population: frequency and risk factors. Circulation 126, 2302–2308.
  109. Curjuric I, Imboden M, Nadif R, Kumar A, Schindler C, Haun M, Kronenberg F, Künzli N, Phuleria H, Postma DS, Russi EW, Rochat T, Demenais F & Probst-Hensch NM (2012) Different genes interact with particulate matter and tobacco smoke exposure in affecting lung function decline in the general population. PLoS One 7, e40175
  110. Thun GA, Ferrarotti I, Imboden M, Rochat T, Gerbase M, Kronenberg F, Bridevaux PO, Zemp E, Zorzetto M, Ottaviani S, Russi EW, Luisetti M & Probst-Hensch NM (2012) SERPINA1 PiZ and PiS heterozygotes and lung function decline in the SAPALDIA cohort. PLoS One 7, e42728
  111. Wanner M, Martin BW, Meier F, Probst-Hensch N & Kriemler S (2012) Effects of filter choice in GT3X accelerometer assessments of free-living activity. Med Sci Sports Exerc (in press).
  112. Wilk JB, Shrine NR, Loehr LR, Zhao JH, Manichaikul A, Lopez LM, Smith AV, Heckbert SR, Smolonska J, Tang W, Loth DW, Curjuric I, Hui J, Cho MH, Latourelle JC, Henry AP, Aldrich M, Bakke P, Beaty TH, Bentley AR, Borecki IB, Brusselle GG, Burkart KM, Chen TH, Couper D, Crapo JD, Davies G, Dupuis J, Franceschini N, Gulsvik A, Hancock DB, Harris TB, Hofman A, Imboden M, James AL, Khaw KT, Lahousse L, Launer LJ, Litonjua A, Liu Y, Lohman KK, Lomas DA, Lumley T, Marciante KD, McArdle WL, Meibohm B, Morrison AC, Musk AW, Myers RH, North KE, Postma DS, Psaty BM, Rich SS, Rivadeneira F, Rochat T, Rotter JI, Soler AM, Starr JM, Uitterlinden AG, Wareham NJ, Wijmenga C, Zanen P, Province MA, Silverman EK, Deary IJ, Palmer LJ, Cassano PA, Gudnason V, Barr RG, Loos RJ, Strachan DP, London SJ, Boezen HM, Probst-Hensch N, Gharib SA, Hall IP, O'Connor GT, Tobin MD & Stricker BH (2012) Genome wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Am J Respir Crit Care Med 186, 622–632
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  115. Eeftens M, Beelen R, de Hoogh K, Bellander T, Cesaroni G, Cirach M, Declercq C, Dedele A, Dons E, de Nazelle A, Dimakopoulou K, Eriksen KT, Falq G, Fischer P, Galassi C, Grazuleviciene R, Heinrich J, Hoffmann B, Jerrett M, Keidel D, Korek M, Lankki T, Lindley S, Madsen C, Molter A, Nador G, Nieuwenhuijsen MJ, Nonnemacher M, Pedeli X, Raaschou Nielsen O, Patelarou E, Quass U, Ranzi A, Schindler C, Stempfelet M, Stephanou EG, Sugiri D, Tsai M, Yli-Tuomi T, Varro MJ, Vienneau D, von Klot S, Wolf K, Brunekreef B & Hoek G (2012) Development of land use regression models for PM2.5, PM2.5 absorbance, PM10 and PMcoarse in 20 European study areas; results of the ESCAPE project. Environ Sci Technol 46, 11195–11205.
  116. Caviezel S, Dratva J, Schaffner E, Schindler C,  Probst-Hensch N, Künzli N, Gaspoz JM, Rochat T & Schmidt-Trucksass A (2012) Association of carotide strain and prior of cardiovascular disease - results from the Swiss Air Pollution and Lung and Heart Disease in Adults Cohort Study (SAPALDIA3). Artery Res 6, 151
  117. Leynaert B, Sunyer J, Garcia-Esteban R, Svanes C, Jarvis D, Cerveri I, Dratva J, Gislason T, Heinrich J, Janson C, Künzli N, de Marco R, Omenaas E, Raherison C, Gómez Real F, Wjst M, Zemp E, Zureik M, Burney PG, Anto JM & Neukirch F (2012) Gender differences in prevalence, diagnosis and incidence of allergic and non-allergic asthma: a population-based cohort. Thorax 67, 625–631.
  118. Rochat T, Bridevaux PO, Gerbase M, Probst-Hensch N & Künzli N (2012) Quel est le rôle de la pollution atmosphérique dans l'asthme? Rev Méd Suisse 8, 2233–2238
  119. Wüthrich B, Schmid-Grendelmeier P, Schindler C, Imboden M, Bircher A, Zemp E, Probst-Hensch N & SAPALDIA TEAM (2013) Prevalence of atopy and respiratory allergic diseases in the elderly SAPALDIA population.  Int Arch Allergy Immunol 162, 45–50
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  123. Canova C, Heinrich J, Anto JM, Leynaert B, Smith M, Künzli N, Zock JP, Janson C, Cerveri I, de Marco R, Toren K, Gislason T, Nowak D, Pin I, Wjst M, Manfreda J, Svanes C, Crane J, Abramson M, Burr M, Burney P & Jarvis D (2013) The influence of sensitisation to pollens and moulds on seasonal variations in asthma attacks. Eur Respir J (in press).
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  126. Beelen R, Hoek G, Vienneau D, Eeftens M, Dimakopoulou K, Pedeli X, Tsai MY, Künzli N, Schikowski T, Marco A, Eriksen K, Raaschou-Nielsen O, Stephanou E, Patelarou E, Lanki T, Yli-Tuomi T, Declercq C, Falq G, Stempfelet M, Birk M, Cyrys J, von Klot S, Nador G, Varro MJ, Dedele A, Grazuleviciene R, Mölter A, Lindley S, Madsen C, Cesaroni G, Ranzi A, Badaloni C, Hoffmann B, Nonnemacher M, Krämer U, Kuhlbusch T, Cirach M, de Nazelle A, Nieuwenhuijsen M, Bellander T, Korek M, Olsson D, Strömgren M, Dons E, Jerrett M, Fischer P, Wang M, Brunekreef B & de Hoogh K (2013) Development of NO(2)and NO(x) land use regression models for estimating air pollution exposure in 36 study areas in Europe - The ESCAPE project. Atmos Environ 72, 10–23
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  129. Wanner M, Probst-Hensch N, Kriemler S, Meier F, Bauman A & Martin BW (2013) What physical activity surveillance needs: validity of a single-item questionnaire. Br J Sports Med (in press).
  130. Wüthrich B, Schmid-Grendelmeier P, Schindler C, Imboden M, Bircher A, Zemp E, Probst-Hensch N & SAPALDIA TEAM (2013) Prevalence of atopy and respiratory allergic diseases in the elderly SAPALDIA population.  Int Arch Allergy Immunol 162, 45–50
  131. Thun GA, Imboden M, Ferrarotti I, Kumar A, Obeidat M, Zorzetto M, Haun M, Curjuric I, Couto Alves A, Jackson VE, Albrecht E, Ried JS, Teumer A, Lopez LM, Huffman JE, Enroth S, Bosse Y, Hao K, Timens W, Gyllensten U, Polasek O, Wilson JF, Rudan I, Hayward C, Sandford AJ, Deary IJ, Koch B, Reischl E, Schulz H, Hui J, James AL, Rochat T, Russi EW, Jarvelin MR, Strachan DP, Hall IP, Tobin MD, Dahl M, Fallgaard Nielsen S, Nordestgaard BG, Kronenberg F, Luisetti M & Probst-Hensch NM (2013) Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels. PLoS Genet 9, e1003585
  132. Gerbase MW, Dupuis-Lozeron E, Schindler C, Keidel D, Bridevaux PO, Kriemler S, Probst-Hensch NM, Rochat T & Künzli N (2013) Agreement between spirometers: a challenge in the follow-up of patients and populations? Respiration 85, 505–514
  133. Rochat MK, Laubender RP, Kuster D, Braendli O, Moeller A, Mansmann U, von Mutius E, Wildhaber J.: Spirometry Reference Equations for Central European Populations from School Age to Old Age. PLoS ONE 2013; 8(1): e52619. doi:10.1371/journal.pone.005261
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  135. Mélen E, Granell R, Kogevinas M, Strachan D, Gonzalez JR, Wjst M, Jarvis D, Ege M, Braun-Fahrländer C, Genuneit J, Horak E, Bouzigon E, Demenais F, Kauffmann F, Siroux V, Michel S, von Berg A, Heinzmann A, Kabesch M, Probst-Hensch NM, Curjuric I, Imboden M, Rochat T, Henderson J, Sterne JAC, McArdle WL, Hui J, James AL, Musk AW, Palmer LJ, Becker A, Kozyrskyj AL, Chan-Young M, Park JE, Leung A, Daley D, Freidin MB, Deev IA, Ogorodova LM, Puzyrev VP, Celedón JC, Brehm JM, Cloutier MM, Canino G, Acosta-Pérez E, Soto-Quiros M, Avila L, Bergström A, Magnusson J, Söderhäll C, Kull I, Scholtens S, Boezen HM, Koppelman GH, Wijga AH, Marenholz I, Esparza-Gordillo J, Lau S, Lee YA, Standl M, Tiesler CMT, Flexeder C, Heinrich J, Myers RA, Ober C, Nicolae DL, Farrall M, Kumar A, Moffatt MF, Cookson WOCM & Lasky-Su J (2013) Genome-wide association study of body mass index in 23,000 individuals with and without asthma. Clin Exp Allergy 43, 463–474.
  136. Thun GA, Imboden M, Berger W, Rochat T, Probst-Hensch NM. (2013) The Association of a Variant in the Cell Cycle Control Gene CCND1 and Obesity on the Development of Asthma in the Swiss SAPALDIA Study. J Asthma. 2013 Mar;50(2):147-54.
  137. Wanner M, Martin BW, Meier F, Probst-Hensch N & Kriemler S (2013) Effects of filter choice in GT3X accelerometer assessments of free-living activity. Med Sci Sports Exerc 45, 170–177
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  141. Dratva J, Probst-Hensch N, Schmidt-Trucksäss A, Caviezel S, de Groot E, Bettschart R, Saleh L, Gapoz JM, Rothe T, Schindler C, Stolz D, Turk A, Rochat T, Künzli N & Zemp E (2013) Atherogenesis in youth - early consequence of adolescent smoking. Atherosclerosis (in press).
  142. Dratva J, Breton CV, Hodis HN, Mack WJ, Salam MT, Zemp E, Gilliland F, Künzli N & Avol E (2013) Birth weight and carotid artery intima-media thickness. J Pediatr 162, 906–911.e2
  143. S. Scholtens, D.S. Postma, M.F. Moffatt, S. Panasevich, R. Granell, J. A. Henderson, E. Melén, F. Nyberg, G. Pershagen, D. Jarvis, A. Ramasamy, M. Wjst, C. Svanes, EGEA co-authors, E. von Mutius, C. Braun-Fahrländer, D. Heederik, J. Genuneit and the GABRIELA study group, B. Brunekreef, H.A. Smit, A.H. Wijga, M. Kerkhof, I. Curjuric, M. Imboden, G.A. Thun, N. Probst-Hensch, M. B. Freidin, E. I. Bragina, I. A.Deev, V. P.Puzyrev, D. Daley, J. Park, A. Becker, M. C.Yeung, A. L. Kozyrskyj, P. Pare, MAS co-authors, M. Kabesch, LifeLines co-authors, A. Kumar, M. Farrall, W.O.C.M. Cookson, D. Strachan, G. H. Koppelman, H. M. Boezen. Genes for childhood asthma identified by interaction with in utero and early childhood smoke exposure: a Genome-Wide Interaction Study. The GABRIEL consortium. in revision Journal of Allergy and Clincal Immunology (in press)
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  145. Valérie Siroux, Juan R González, Emmanuelle Bouzigon, Ivan Curjuric, Anne Boudier, Isabelle Pin, Medea Imboden, Deborah Jarvis, Florence Demenais, Nicole Probst-Hensch, Manolis Kogevinas, Francine Kauffmann. Genome-wide association study on adult asthma phenotypes identified by a clustering approach.  European Respiratory Journal (in press)
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